Membrane 'neighborhood' helps transporter protein regulate cell signaling

Phys.org12/7/2025 • Last cited 12/14/2025

Summary

A study published by Phys.org reveals that the protein ABCC4 plays a crucial role in regulating the levels of cyclic AMP (cAMP) within cells, ensuring that signals are accurately transmitted without unintended activation of other pathways. The research highlights the importance of ABCC4's positioning in maintaining local control of cAMP, although the exact mechanisms of its localization remain unclear.

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Lindy Score Breakdown

35
Age (0-35)
39 days
4
Velocity (0-40)
1 source (low traction)
6
Tier (0-10)
Phys.org
0
Breadth (0-15)
1 unique
Total Score45/100

Score BreakdownRisk 50

Source Reputation: Low-trust source (6/20 pts)
Consensus: Single source - no independent confirmation yet
Age: 39 days - proven survivor

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