Oliver Sacks on Despair and the Meaning of Life

‘What are we doing here?’ The polymaths who searched for the meaning of life

How Not to Waste Your Life

New AI model could cut the costs of developing protein drugs

The New Global Order

Are we hard-wired for infidelity?

Open Thread

Dogs Can Have Dementia, Too

Pulsar Found Near the Center of the Milky Way Could Test Einstein’s Theories

Giant Pythons Once Roamed Prehistoric Taiwan

Spaceflight literally moves your brain

Penny, a Doberman pinscher, wins the Westminster dog show

The Monarchs, Music, and the Meaning of Life: The Most Touching Deathbed Love Letter Ever Written

Sleep and the Meaning of Life: Fernando Pessoa on the Existential Dimension of the Horizontal Hours

Yes to Life, in Spite of Everything: Viktor Frankl’s Lost Lectures on Moving Beyond Optimism and Pessimism to Find the Deepest Source of Meaning

Dostoyevsky, Just After His Death Sentence Was Repealed, on the Meaning of Life

Albert Camus on the Three Antidotes to the Absurdity of Life

The war between writers and editors can be long, brutish, and nasty. "Every semicolon was a matter of life or death”

A Life of One’s Own: A Penetrating Century-Old Field Guide to Self-Possession, Mindful Perception, and the Art of Knowing What You Really Want

The Original Meaning of Birthright Citizenship

Darwin’s Greatest Regret and His Deathbed Reflection on What Makes Life Worth Living

The Leaf that Wouldn’t Fall: A Tender Illustrated Parable about the Measure and Meaning of Love