CRISPR’s next act: the companies editing the epigenome to treat disease

Does Nurture Trump Nature in Disease Risk Prediction?

The Good, the Bad, and the Uncanny: Some Notes on Wearables

Cities Show How Climate Action Makes Life Better

Mamdani’s Selective Socialism

Listening for the echoes of black holes

The Meaning of Ro Khanna

The Renaissance didn't begin in Florence. It began six thousand years ago in the Middle East. So argues a new book

Open Thread

Is the Twenty-First Century a Creative Void?

Thursday Poem

Britain’s Next Leader Has Emerged

The Tech Companies That Just Need the Money

Buildings May Soon Have ‘Immune Systems’ That Fight Airborne Disease

Open Thread

Why U.K. Socialism Could Soon Be America's Problem

The Secret Origins of 'Conspiracy Theory'

When the blogosphere gave way to Substack, writers gained audiences but lost each other. Noah Smith explains

Dinosaurs, crocodilo-pythons, and other monsters populated the “lost world” novels that thrived between the 1880s and 1920s

Open Thread

Open Thread