Lung cancers can use two different mechanisms to evade KRAS-inhibiting drugs

The Way the FDA and DEA Ban Drugs Is Unaccountable and Arbitrary

Why Did Wallace Shawn Liken Israelis to Nazis?

Upon publication of The Last Samurai, a suicidal Helen DeWitt disappeared. She was, she says, “alienated by intellectual mediocrity”

Second Amendment Roundup: Bruen's Footnote 9 Not a Carve-Out from Text and History

Mahmoud Khalil: Imprisoned for no crime, I discovered my arrest was a message

“The word ‘audiophile’? has a wine-sipping pretension that I hate,” says Colin Vanderburg. “But sometimes an ugly shoe fits”

Review of “The Complex” by Karan Mahajan – a superb family saga set in Delhi

SCOTUS Stays Third-Party Removal Injunction 40 Minutes After Reply Filed

Beware the Rush to Judgment in the Cornell Rape Case

No Sealing of Property Information in Motion Challenging Diversity Jurisdiction

Open Thread

Today in Supreme Court History: September 26, 1986

A Russia Sanctions Bill Would Give Trump Vast New Tariff Powers

The AI Tipping Point

Today in Supreme Court History: September 27, 1787

The Cost of Not Building Data Centers

OpenAI Preaches AI Safety. The Australia Incident Shows What It Practices.

Today in Supreme Court History: September 25, 1981

Dario Amodei, Sam Altman, Yoshua Bengio, and others brief UN Security Council on AI risks

Advisory Group on Mathematics and Artificial Intelligence